To run multiple pumps on a single return line would require check valves on each pump's line to be successful. Otherwise, the water from the pump left working will take the path of least resistance and back-flow through the non-working pump, because it is lower than the aquarium return (less head pressure). I'm assuming you have 2 pumps joined with a Y or T in this scenario?
Or, are you considering running them in series? If so, the pump left running would have to push against the dead pump's impeller, with reduced flow.
That being said, I have run check valves before but would not do so again. Just one more thing to fail that I can eliminate.
Otherwise, it is possible under something like this-
I have 3 in my system. Each feeds a different tank. There are 3 tanks, a common sump and separate refugium with total volume of 140 gallons. Each pump has it's own return line.