The only time I like a stand alone control option is with lighting. It can be nice to have one quick place to handle that. But pumps/powerheads on multiple interfaces is a royal PITA. I hate Mobius and it sucks not having another choice.
The Hydros WaveEngine seems to be a pretty good product. I will be playing with it soon. But there is no option to control Vectra's on HWE and something tells me that the new conglomerate will not play nice with CoralVue which sucks.
It's not good for us to have all of our eggs in one basket. An Apex base unit dies and the whole system is shut down. Then to have to scramble to find outlets, power strips and go into emergency mode. The only other potion is to have a backup base unit sitting on a shelf, fortunately I have one. But you have to keep the firmware up to date and keep a backup of your programming every time you change something. You also need to keep a pdf copy of every module you have and connect them to the backup base unit in the exact same order that they were originally connected. Forget to do either of those and you will be stuck for a long time programming.
It's also a PITA that Neptune doesn't allow us to manually change module addresses. At the very least an option in Fusion to select the address when a new module is first connected.