What I did with the inside of my stand is used a PVC liner--it's thick, durable, flexible sheeting used for shower/bath liners, and sold relatively cheap at Lowe's/HD. The great advantages of doing this are that it's smooth (no wrinkles) and easy to clean/wipe up spills, there's no grout to worry about, and you can actually use PVC cement to seal any seams. I used tack nails to tack it down to the bottom/sides of my stand, and PVC cement around a central drain line that goes through the floor into my crawlspace for emptying the tank or doing water changes.
This liner has been great, and has prevented gallons of water from getting onto my hardwoods (120 year old heart pine floor...)
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