Flow is flow, I calculate my returns. On a larger tank it's more efficient to create flow with propeller type pumps but if they don't fit in your small tank you can get away with using your return. A lot of nano's are set up like that
I used a mag 12 and a scwd on a 22g sps tank with great results. The thing you need to worry about is micro bubbles if your using a sump thats too small to handle that kind of flow. I used a 36in MRC reef sump that held 30g of water connected to my 22g cube so I had no issues using a large return pump. Also I would use true union ball valves on that scwd to make it easy to take off and clean, they seem to get jammed up rather easy.
Of course if you have the money then I would get a nano stream 6055 and a single controller or wait for the new vortech mp20 to come out. Then you could use a very small return pump(100-200gph) and save some money on the power bill.