well ive never changed water in anything bigger than my 30 (i guess i changed my 125 but that was FW so a bit diff) but yeah....i personally shut off everything, especially your return pump. Also, pumps/ PH's thats come out of the water because of the drop in your water level.
Of course, do the wc as fast as possible and try not leave any corals out of the water for too, too long.
I know some people with big tanks just do a wc in their sump and not in the main display. If thats the case, you can leave all the PH's and stuff on and if your heater is in your display you leave that on too and that way time doesnt really become a factor.
good luck.