I'm an advocate of stability. Nearly all living creatures do better in a stable environment. I have an automated WC system that replaces 30g a week on a 200g twv system. Every 3 hours about a half gallon is pumped out of the tank and a half gallon of new SW is pumped in.
Take something you can measure/monitor in the tank as an example. PH- The ideal PH we strive for is 8.4. Is it better to occasionally spike the system from it's normal PH of let's say 8.1 to 8.4 since that's the ideal PH or keep it a constant 8.1?
I say keep it a constant 8.1
While 8.4 may be an ideal level, it's only ideal if it's maintained.
Same applies for everything on your tank. Lighting, specific gravity, temperature, PO4 levels, etc. While each one of these things have "ideal" set points, it's better to keep any given one steady at a less than ideal set point than to spike it up and down trying to achieve perfection.
Large water changes can throw so many harmonic balances in the tank out of whack quickly. While this may not keep you from having a successful reef tank, success is a relative term. Some people's tanks are able to keep difficult creatures THRIVING when others can either not keep them at all. So many variables can contribute to this but the more things you can keep consistent in the tank, the better off the tank will be in the long run.
Edit: Dang people, I can't get my response typed out before you guys echo it.