http://uskoi.com/prazipro.htm">http://uskoi.com/prazipro.htm</a>
Directions For Use:
For treatment of praziquantel-susceptible disease conditions in pond, freshwater and marine aquariums.
As A Bath: Start treatment with as large a water change as practical or start with new water. Any water used should first be conditioned with ULTIMATE® or a combination of Liquid Buffered ClorAm-X® and Stress-X™ to remove ammonia, chlorine and chloramines. [B]Do not stop filtration, but remove activated carbon and stop foam-fractionation (protein skimming) and UV sterilization.[/B] Shake vigorously before use. Measure Aquarium Solutions® Liquid PraziPro® at the rate of one (1) teaspoon per 20 gallons of water to be treated. (one (1) fl. oz. per 120 gallons) Measure Pond Solutions™ Liquid PraziPro® at the rate of one (1) teaspoon per 32 gallons of water to be treated. (one (1) fl. oz. per 200 gallons) This produces a concentration of 2.5 mg/L. Distribute the proper amount around the edge of the aquarium or pond or directly in to the filter box to achieve the best overall distribution. [B]A single treatment lasting 5-7 days is normally sufficient.[/B] Repeat as necessary, but no more than once every 3 to 5 days. May be used as a preventative, at the standard dosage, when disease is likely. Do not use with other drugs or disease treatments. May cause temporary foaming.
Edit: basically, turn your skimmer off!