There was a very long thread on UV which was pinned at the top of reef discussion (or similar forum name) on the old ARC site. I've been gone awhile, but will summarize-
How it works: In a nutshell, UV (approximately 290 nM wavelength) damages a specific bond in thymine, one of the four bases which make up DNA.
How much you need: This depends on several factors, including: flow, target organism(s), water turbidity, UV device geometry, etc.
The highest irradiance requirements to control aquatic pathogens I found published is for cryptocaryon irritans at 280,000 µWsec/cm2+(to over 800,000µWsec/cm2). This level may vary widely, has been extrapolated from other organisms (or is anecdotal) and is stated by UV filter manufacturers which mostly market themselves as water treatment companies
based on a single pass treatment, as is
required for drinking water. The efficacy actually depends on a statistical probability of the thymine bonds intercepting a UV photon.
Why does that matter to us? Because in an aquarium, we recirculate the same water (& organisms) through the UV device potentially multiple times. So, the probability of interception increases with time.
On the other hand, UV bulbs degrade with time (lowering their output), bulbs get dirty, etc.
All in all, a good argument can be made that the published power requirements (eg- watts per gallon) may be overkill.
The counter argument has been made that: Excess (ie- oversized) UV won't hurt anything (except your wallet!).
More info., related to sun damage, but still applies-
"When UVB light hits the DNA strand, it causes a change in the structure of the chain. Any place along the strand that has two thymine bases in a row is vulnerable to this damage. The energy of the UVB light alters a chemical bond in the thymine. The altered bond causes the neighboring thymine bases to stick to each other. This pair of stuck-together thymine molecules is called a dimer. Wherever these dimers are formed, the DNA strand is bent from its normal shape, and cannot be read properly by the cell. Every second a cell is exposed to the UVB in sunlight can cause the creation of up to 100 dimers. If a cell accumulates too many dimers, it can die or become cancerous."
https://sciencing.com/uv-light-damage-dna-strand-12687.html
For cryptocaryon control-
http://edis.ifas.ufl.edu/pdffiles/FA/FA16400.pdf